Routine Flash Chromatography

Complex technologies hidden behind a simple button take your Flash chromatography to another dimension.

Routine Flash chromatography or more complex purifications?

The Interchim range of instruments is designed to always be synonymous with success, whatever the difficulty.

Maximum technology and the full, globally recognized know-how are incorporated into these purification systems. Choosing a puriFlash® system therefore means benefiting from state-of-the-art technology with a minimum of space required. This guarantees optimization of your working time and increased safety for your samples.

Increase your productivity and trust your purification system to work 24 hours a day, 7 days a week.

Below you will find our solutions from Routine Flash Chromatography to Ultra Performance Flash chromatography.

puriFlash XS 520 Plus

Bundled technology for unsurpassed performance.
Both the unique technology and the quality of the pump bring you a significant step forward in routine flash chromatography. Even with increased pressure, the puriFlash® XS 520 Plus system offers the same precision, linearity and reproducibility and enables advanced purification. You have high standards and so do we. That’s why Interchim has combined all their purification expertise into one system that is as compact as its price.

  • Control unit
  • Pump
  • UV detector
  • Fraction collector
  • Solvent tray with drainage system
  • Integrated column holder
  • Stainless steel needle with connection (54 mm)
  • Flow range: 1 mL/min to 300 mL/min
  • Max. operational flow rate: 300 mL/min
  • Optimal flow rate for columns up to 800G
  • Flow accuracy: +/- 2% over 20 to 250 mL/min & 5 to 16 bar
  • Repeatability of the flow: < 0.25
  • Linearity of the flow: 0.98 < linearity < 1
  • Pressure range: 0 to 20 bar
  • Max. operating pressure: 20 bar
  • Quaternary gradient valve
  • Gradient tolerance step: < 3.5 %
  • Air purge
  • Injection mode: liquid or solid
  • “Load & Go” technology: staggered Dry-Load for even more efficient injections automated via a 4-port electric valve (included in the Pack-Ultra)
  • UV detector 200-400 nm
  • “DAD” technology
  • Multi-wavelength and scan over a width of 600 nm
  • Spectral visualization and confirmation of purity
  • Cell for optical path length 0.3mm

puriFlash 5.020

An instrument specifically for ultra-efficient Flash Chromatography (Ultra Performance Flash Purification)
With a maximum flow rate of up to 300 ml/min, the puriFlash® 5.020 allows you to easily use columns in sizes F0004 to F0800 (4 to 800 g) at optimal flow rates to purify different amounts of product.

In combination with the puriFlash® 15 μm columns, you will also save yourself a lot of time. Use flows higher than the optimum flow for faster purifications with an extremely low loss of efficiency and reduce your purification time by up to 50%.

Like all Interchim purification systems, the puriFlash® 5.020 is an instrument designed with minimum space requirements and equipped with the most advanced technology to make everyday life even more enjoyable.

Automation was central to the design process, reducing the risk of errors during purification by detecting connections, possible leaks and solvent fill levels. But also to give you unparalleled working comfort; for example, through the automatic detection of columns, racks and dry-load via the InterSoft X software.

  • Control unit
  • Pump
  • UV detector
  • Fraction collector
  • Solvent tray with drainage system
  • Integrated column holder
  • Stainless steel needle with connection (54 mm)
  • Flow range: 1 mL/min to 300 mL/min
  • Max. operational flow rate: 300 mL/min
  • Optimal flow rate for columns up to F0800 (800grams)
  • Flow accuracy: +/- 2% over 20 to 200 mL/min & 5 to 16 bar
  • Repeatability of the flow: < 0.25
  • Linearity of the flow: 0.98 < linearity < 1
  • Pressure range: 0 to 20 bar
  • Maximum working pressure: 20 bar
  • Quaternary gradient valve
  • Gradient tolerance step: < 3.5 %
  • Air Purge
  • Injection mode: liquid or solid
  • “Load & Go” technology: staggered Dry-Load for even more efficient injections automated through a 4-port electric valve
  • RFID technology: automatic detection of the Dry-Load
  • UV detector 200-400 nm
  • UV detector 200-800 nm (included in Pack-UVextended)
  • “DAD” technology
  • Multi-wavelength and scan collection over a band of 200 nm (or 600 nm with Pack-UVextended)
  • Spectral visualization and confirmation of purity
  • Flow cell path: 0.3 mm/ 40 µL
  • Integrated ELSD detector (included in Pack-iELSD)

puriFlash 5,020 5X

Compactness, multi-columns, sequential purification
With its 5-column supports, all you have to do is install your columns to create your methods and inject your products to be purified, and your puriFlash® 5.020 5X’s InterSoft X software will automatically start your methods one after the other, ensuring higher productivity. In addition, this unique device reduces work space.
After each method, the tubes are rinsed to prevent contamination from one purification to the next.

Thanks to a 6-way automatic injection valve, connected to an autosampler, it will be possible to automatically inject the desired column with the sample to be purified.

Thanks to the RFID technology available for the columns, racks and the injection loop, InterSoft X integrates the parameters into your method that are essential for the success of your purification. Added to this technology are multiple detectors for potential leaks, giving you maximum technology in minimum space and improved safety. Remove your puriFlash® 5,020 5X, equipped with an exhaust hood, from the fume hood to free up space for your syntheses.

  • Control unit
  • Pump
  • UV detector
  • Fraction collector
  • Solvent tray with drainage system
  • 5 integrated column holders
  • Flow range: 1 mL/min to 300 mL/min
  • Max. operational flow rate: 300 mL/min
  • Optimal flow rate for columns up to F0800 (800grams)
  • Flow accuracy: +/- 2% over 20 to 200 mL/min & 5 to 16 bar
  • Repeatability of the flow: < 0.25
  • Linearity of the flow: 0.98 < linearity < 1
  • Pressure range: 0 to 20 bar
  • Maximum working pressure: 20 bar
  • Quaternary gradient valve
  • Gradient tolerance step: < 3.5 %
  • Air Purge
  • Injection mode: liquid or solid
  • “Load & Go” technology: with automatic 6-way valve allowing the use of a loop for even more efficient injection
  • 2 ml stainless steel loop with RFID tag
  • UV detector 200-400 nm
  • UV detector 200-800 nm (included in Pack-UVextended)
  • “DAD” technology
  • Multi-wavelength and scan collection over a band of 200 nm (or 600 nm with Pack-UVextended)
  • Spectral visualization and confirmation of purity
  • Flow cell path: 0.3 mm/ 40 µL
  • Integrated ELSD detector (included in Pack-iELSD)

puriFlash 5.050

Performance and versatility in any situation.

The puriFlash® 5,050 is a unique instrument for successfully performing preparative and flash chromatography, switching from normal phase to Reversed Phase and working with reusable columns. And ultimately a more ecological approach to purification.

Achieve higher/greater purity.
With a maximum pressure of 50 bar, this is the ideal device to access preparative chromatography while performing flash purification.
Indeed, for more complex reprocessing in Reversed Phase, the use of stainless steel columns filled with low particle size phases is the tool of choice for successful separations.

  • Control unit
  • Pump
  • UV detector
  • Fraction collector
  • Solvent tray with drainage system
  • Integrated column holder
  • Integrated Dry-Load holder
  • Flow range: 1 mL/min to 250 mL/min
  • Maximum operational flow rate: 250 mL/min
  • Optimal flow rate for columns up to F0800 (800grams)
  • Flow accuracy: +/- 2% over 20 to 200 mL/min & 5 to 40 bar
  • Repeatability of the flow: < 0.25
  • Linearity of the flow: 0.98 < linearity < 1
  • Pressure range: 0 to 50 bar
  • Maximum working pressure: 50 bar
  • Quaternary gradient valve
  • Gradient tolerance step: < 3.5 %
  • Air Purge
  • Washing Discs
  • Injection mode: liquid or solid
  • “Load & Go”: with automatic 6-way valve allowing the use of staggered Dry-Load or a loop for even more efficient injection
  • RFID technology: automatic detection of the Dry-Load and the injection loop
  • 2 mL stainless steel injection loop with RFID tag
  • UV detector 200-400 nm
  • UV detector 200-800 nm (included in Pack-UVextended)
  • “DAD” technology
  • Multi-wavelength and scan collection over a band of 200 nm (or 600 nm with Pack-UVextended)
  • Spectral visualization and confirmation of purity
  • Flow cell path: 0.3 mm/ 40 µL
  • Integrated ELSD detector (included in Pack-iELSD)

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