Peptide & Oligonucleotide Flash Systems

Purification of peptides or oligonucleotides
Whether it’s Flash chromatography or Preparative chromatography, Interchim’s compact instruments will meet all your needs.
Equipped with multiple controls, increased safety and proven technology, these specialized peptide or oligonucleotide instruments are designed to give you unparalleled reliability.

“Genius”, the artificial intelligence built into the InterSoft X software, will guide you to get out of even your most complex purifications. Be prepared for unsurpassed performance.

Applications:

  • Small organic molecules
  • Detection of impurities
  • Natural products
  • Peptides and oligonucleotides
  • Proteins and biopharmaceuticals
  • Isolation of metabolites
  • Trace enrichment

puriFlash 5.250P

Complex chromatography of peptides and oligonucleotides never been easier.
The PuriFlash® 5,250P, designed for the demanding purification of peptides and oligonucleotides in preparative and Flash chromatography. The use of small particle sizes combined with reduced dead volume makes it possible to distinguish closely spaced peptides and oligonucleotides in terms of amino acid sequences.

The PuriFlash® 5,250P separates compounds with very short retention times time after time and achieves unmatched results for complex chromatography of peptides and oligonucleotides. The combination of the UV cell with an optical path length of 1.3 mm and with a reduced dead volume makes it possible to detect compounds in small amounts or with weak extinction.

See all your components and don’t lose any of them.
Thanks to the different detection methods available, you will not lose the overview during chromatography, because the triple detection methods – UV, ELSD and mass – guarantee the visibility of all your components. The fine parameter control of the detection technologies used ensures maximum purification efficiency without loss of product.

  • Control unit
  • Pump
  • UV detector
  • Fraction collector
  • Solvent reservoir
  • Integrated column holder (2 pcs)
  • Integrated Dry Load holders (2 pcs)
  • Flow: 125 mL/min
  • Optimal flow rate for columns with an internal diameter of up to 60 mm
  • Maximum pressure: 250 bar
  • Quaternary gradient valve
  • Venting
    Washers and wash pump (circulates water to prevent deposition of crystals on pump pistons)
  • Injection mode: liquid or solid
  • “Load & Go” technology: with automatic 10-way valve allowing the use of staggered Dry Load or injection loops for more efficient injection
  • “RFID technology”: automatic detection of Dry Loads and injection loops
  • Stainless steel injection loops of 2mL and 5mL
  • UV detector 200-400 nm
  • UV detector 200-800 nm (included in UVextended package)
  • “DAD” technology
  • Multi-wavelength and scan over a band of 200 nm (or 600 nm with  UVextended package)
  • Spectral visualization and confirmation of purity
  • Optical path length of cell: 1.3 mm
  • Integrated ELSD detector (included in iELSD package)

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